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Nitrogen fixation converts N₂ toward biologically usable reduced nitrogen; ammonification, nitrification and denitrification transform nitrogen among distinct chemical pools.
ModelBiologyBiodiversity and conservation evidenceBiodiversity includes genetic, species and ecosystem dimensions.
DefinitionEarth & cosmos · BiologyFossils, correlation and palaeoenvironmentFossil assemblages can constrain relative age and depositional environment through observed succession and known ecological context.
MethodEarth & cosmos · Chemistry · BiologyWeathering, soil formation and chemical exportMechanical weathering changes fragment size; chemical weathering transforms or dissolves minerals through reactions such as hydrolysis and oxidation.
ModelEarth & cosmos · Chemistry · BiologyMarine carbonate speciation and exchangeDissolved inorganic carbon includes aqueous CO₂/carbonic-acid convention, bicarbonate and carbonate.
ModelBiology · ChemistrytRNA charging and editingAminoacyl-tRNA synthetases couple amino acids to cognate tRNAs using ATP-dependent activation.
ModelBiologyTranslation initiation and start-site selectionCanonical eukaryotic initiation recruits a small ribosomal complex near the capped mRNA end and scans for a start codon in a suitable context.
ModelBiologyEnhancers and regulated transcription complexesEnhancer-bound activators can influence a promoter through protein interactions, including Mediator and chromatin-remodelling or modifying complexes.
ModelBiologySignal recognition and ER translocationIn the canonical secretory route, SRP recognizes an emerging signal sequence and targets the ribosome–nascent-chain complex to the ER receptor and Sec61 channel.
ModelBiologyMitochondrial protein targeting and importMany nuclear-encoded mitochondrial matrix proteins carry targeting sequences recognized by TOM and transferred through the TIM23 pathway.
ModelBiologyRab-guided targeting and SNARE fusionRab GTPases and effectors help recruit and tether transport carriers at appropriate membranes.
ModelBiologyHeterotrimeric G-protein receptor cycleAn activated GPCR promotes GDP release and GTP binding on a heterotrimeric G protein's α subunit.
ModelBiologyReceptor tyrosine kinase and Ras signallingActivation of a receptor tyrosine kinase can create phosphotyrosine docking sites for adaptors and enzymes.
ModelBiologyLigand-regulated nuclear receptorsMembers of the nuclear-receptor family bind suitable intracellular ligands and regulate target-gene transcription through DNA-binding and co-regulatory interactions.
ModelBiology · ChemistryProtein folding, environment and chaperonesA protein sequence and its chemical environment constrain a conformational energy landscape.
ModelBiology · ChemistryRubisco oxygenation and photorespiratory salvageRubisco's oxygenase activity produces a three-carbon phosphoglycerate and a two-carbon phosphoglycolate from RuBP.
ModelBiology · ChemistryC4 and CAM carbon-concentrating strategiesIn a common C4 route, PEP carboxylation supplies four-carbon acids that deliver CO₂ to Rubisco in a spatially separated compartment.
ModelBiologyChloroplast export, storage and sink supplyChloroplast triose-phosphate exchange with inorganic phosphate connects photosynthetic fixation to cytosolic sucrose synthesis.
ModelBiologyAnimal body-plan characters and phylogenetic limitsSymmetry, germ layers, body cavities and segmentation describe different aspects of animal organization.
DefinitionBiologySponge feeding and cellular organizationMany sponges pump water through pores and feeding chambers using choanocyte flagella, capturing particles at the collars for intracellular digestion.
ModelBiologyCnidarian tissues, digestion and life cyclesCnidarians characteristically possess cnidocytes with specialized discharge organelles, tissue layers around a gastrovascular cavity and a distributed nervous system.
ModelBiologyMolluscan regions and annelid segmentationA typical molluscan organization comprises a mantle, visceral mass and a muscular foot whose form can be strongly modified.
ModelBiologyEcdysozoan molting and comparative body systemsEcdysozoans replace an external cuticle through molting and ecdysis.
ModelBiologyEchinoderm and chordate comparative organizationEchinoderms characteristically have a calcareous internal skeleton and a water vascular system associated with tube feet; typical adults are pentaradial even though their ancestry lies within bilaterian animals.
ModelBiologyMeiotic gametogenesis and cytoplasmic asymmetryGametogenesis combines germ-cell proliferation, meiosis and cellular differentiation.
ModelBiologyOrganismal heat exchange and thermal regulationBody heat exchange involves radiation, evaporation, convection and conduction.
ModelBiologyPlant meristems, primary growth and secondary tissuesPlant growth combines cell production in meristems with expansion and differentiation.
ModelBiologyMutation flow and two-allele equilibriumMutation transfers allele copies between states.
ModelBiologyGene flow by migrant replacementIf migrants form a specified fraction of a population's allele pool, the post-migration allele frequency is a weighted average of resident and migrant frequencies.
ModelBiologyRecurrent mutation and purifying selectionRecurrent mutation can replenish a deleterious allele that purifying selection removes.
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