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Cell theory describes the organization and reproduction of cellular life.
ModelBiologyDNA and sequence informationDNA's base sequence stores biological information.
DefinitionBiologyGene expressionGene expression produces functional RNA or protein from gene information.
DefinitionBiologyDNA replicationComplementary base pairing allows DNA strands to serve as copying templates.
ModelBiologyCell cycle, mitosis and cytokinesisDNA duplication, nuclear division and cytoplasmic division are distinct events in a typical mitotic cycle.
ModelBiologyMeiosis and chromosome segregationTypical diploid meiosis halves the number of chromosome sets through two divisions after one DNA replication.
ModelBiologyAlleles and Mendelian segregationA diploid individual's paired alleles can segregate into gametes.
ModelBiologyBiological evolutionEvolution concerns inherited change across generations.
DefinitionBiologyNatural selectionHeritable variation can change through differences in reproductive contribution.
ModelBiologyGenetic driftChance can change allele frequencies independently of an adaptive advantage.
ModelBiologyCommon ancestry and branching lineagesEvolutionary relationships describe descent from shared ancestors.
ModelBiology · ChemistryMetabolism and chemical pathwaysMetabolism comprises the regulated chemical reactions of living systems.
DefinitionBiologyOxygenic photosynthesisOxygenic photosynthesis couples light-energy capture to carbon fixation and releases oxygen from water.
ModelBiologyAerobic cellular respirationAerobic respiration couples nutrient oxidation to ATP production, using oxygen as the final electron acceptor.
ModelBiologyMembranes and transportSelective membranes and transport proteins regulate movement between a cell and its surroundings.
ModelBiologyEcology and ecosystemsEcology examines organisms' interactions with one another and their physical environment.
DefinitionBiologyHomeostasis and negative feedbackFeedback can maintain internal variables within functional ranges.
ModelEarth & cosmos · Biology · ChemistryEarth's carbon cycleCarbon moves through biological, oceanic, atmospheric and geological reservoirs.
ModelBiologyMajor biomolecule classesCarbohydrates, lipids, proteins and nucleic acids organize much of cell chemistry.
DefinitionBiologyProtein structure and molecular functionSequence, folding and assembly provide different levels of protein description.
ModelBiologyMichaelis–Menten enzyme kineticsA simple enzyme–substrate mechanism predicts saturating initial rates.
ModelBiologyATP hydrolysis and energy couplingCoupled reaction pathways connect favourable chemistry with cellular work.
ModelBiologyMutation and sequence variationMutation changes DNA sequence and can introduce inherited variation.
DefinitionBiologyGene flow between populationsMovement contributes to gene flow when genetic material enters a population's reproduction.
ModelBiologyExtensions to simple Mendelian inheritanceAllele segregation and phenotype dominance are different questions.
ModelBiologyTranscriptional regulationDNA-binding regulators and cellular signals affect transcription.
ModelBiologyEpigenetic marks and gene regulationDNA-associated marks can affect expression without changing DNA sequence.
ModelBiologySpecies concepts and their limitsSpecies boundaries depend on the organisms and the question being investigated.
DefinitionBiologySpeciation and reproductive isolationReduced reproductive exchange can permit populations to diverge into lineages.
ModelBiologyPhylogenetic inference from charactersEvolutionary trees are hypotheses inferred from comparative evidence.
Method