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Canonical eukaryotic initiation recruits a small ribosomal complex near the capped mRNA end and scans for a start codon in a suitable context.
ModelBiologyEnhancers and regulated transcription complexesEnhancer-bound activators can influence a promoter through protein interactions, including Mediator and chromatin-remodelling or modifying complexes.
ModelBiologySignal recognition and ER translocationIn the canonical secretory route, SRP recognizes an emerging signal sequence and targets the ribosome–nascent-chain complex to the ER receptor and Sec61 channel.
ModelBiologyMitochondrial protein targeting and importMany nuclear-encoded mitochondrial matrix proteins carry targeting sequences recognized by TOM and transferred through the TIM23 pathway.
ModelBiologyRab-guided targeting and SNARE fusionRab GTPases and effectors help recruit and tether transport carriers at appropriate membranes.
ModelBiologyHeterotrimeric G-protein receptor cycleAn activated GPCR promotes GDP release and GTP binding on a heterotrimeric G protein's α subunit.
ModelBiologyReceptor tyrosine kinase and Ras signallingActivation of a receptor tyrosine kinase can create phosphotyrosine docking sites for adaptors and enzymes.
ModelBiologyLigand-regulated nuclear receptorsMembers of the nuclear-receptor family bind suitable intracellular ligands and regulate target-gene transcription through DNA-binding and co-regulatory interactions.
ModelBiology · ChemistryProtein folding, environment and chaperonesA protein sequence and its chemical environment constrain a conformational energy landscape.
ModelBiology · ChemistryRubisco oxygenation and photorespiratory salvageRubisco's oxygenase activity produces a three-carbon phosphoglycerate and a two-carbon phosphoglycolate from RuBP.
ModelBiology · ChemistryC4 and CAM carbon-concentrating strategiesIn a common C4 route, PEP carboxylation supplies four-carbon acids that deliver CO₂ to Rubisco in a spatially separated compartment.
ModelBiologyChloroplast export, storage and sink supplyChloroplast triose-phosphate exchange with inorganic phosphate connects photosynthetic fixation to cytosolic sucrose synthesis.
ModelChemistrySeparability of molecular partition contributionsA molecular internal partition function sums the Boltzmann weights and degeneracies of its internal states.
ApproximationChemistryRigid-rotor rotational partition functionA linear rigid rotor has rotational levels proportional to J(J+1), with magnetic degeneracy 2J+1.
ApproximationChemistryHarmonic vibrational partition and energy zeroFor one harmonic normal mode, a geometric sum gives its vibrational partition function.
ApproximationChemistryRotational and vibrational electric-dipole spectraIn an electric-dipole description, a pure rotational transition requires a molecular permanent dipole, while a normal-mode vibrational transition requires a changing dipole along that coordinate.
ModelChemistryFranck–Condon vibrational overlapAn electronic transition is fast relative to nuclear motion, so its initial nuclear coordinates are approximately unchanged during the transition.
ApproximationChemistryDiffusive chemical transport and mass continuityIn an isotropic Fickian transport model, diffusive mass flux is proportional to the negative local mass-density gradient.
ModelChemistryRepresentations, characters and normal-mode reductionMatrices representing symmetry operations on a chosen basis must reproduce group composition.
MethodChemistrySymmetry selection of IR and Raman modesA transition matrix element ⟨initial|O|final⟩ can be nonzero only when Γinitial*⊗Γoperator⊗Γfinal contains the totally symmetric representation.
MethodBiologyAnimal body-plan characters and phylogenetic limitsSymmetry, germ layers, body cavities and segmentation describe different aspects of animal organization.
DefinitionBiologySponge feeding and cellular organizationMany sponges pump water through pores and feeding chambers using choanocyte flagella, capturing particles at the collars for intracellular digestion.
ModelBiologyCnidarian tissues, digestion and life cyclesCnidarians characteristically possess cnidocytes with specialized discharge organelles, tissue layers around a gastrovascular cavity and a distributed nervous system.
ModelBiologyMolluscan regions and annelid segmentationA typical molluscan organization comprises a mantle, visceral mass and a muscular foot whose form can be strongly modified.
ModelBiologyEcdysozoan molting and comparative body systemsEcdysozoans replace an external cuticle through molting and ecdysis.
ModelBiologyEchinoderm and chordate comparative organizationEchinoderms characteristically have a calcareous internal skeleton and a water vascular system associated with tube feet; typical adults are pentaradial even though their ancestry lies within bilaterian animals.
ModelBiologyMeiotic gametogenesis and cytoplasmic asymmetryGametogenesis combines germ-cell proliferation, meiosis and cellular differentiation.
ModelBiologyOrganismal heat exchange and thermal regulationBody heat exchange involves radiation, evaporation, convection and conduction.
ModelBiologyPlant meristems, primary growth and secondary tissuesPlant growth combines cell production in meristems with expansion and differentiation.
ModelBiologyMutation flow and two-allele equilibriumMutation transfers allele copies between states.
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