Flux-balance feasible spaces and objectives
Research context
postgraduate concept · conditional · As of 2026-10-10
Flux balance imposes steady-state stoichiometric constraints and bounds on reaction rates, then selects fluxes using an objective or additional constraints.
Key knowledge
Flux balance imposes steady-state stoichiometric constraints and bounds on reaction rates, then selects fluxes using an objective or additional constraints. Multiple feasible fluxes may fit the same external measurements; an optimum is not an observed intracellular flux.
Values and equations
S*v = 0; l_j <= v_j <= u_j
- S
- species-by-reaction stoichiometric matrix 1
- v
- reaction-flux vector in a consistent normalization mol s^-1
- l_j
- reaction lower flux bound mol s^-1
- u_j
- reaction upper flux bound mol s^-1
Conditions and scope
- Metabolic steady state and boundary uptake/secretion must be justified; biomass objectives and thermodynamic constraints are model choices.
Sources · 1
References
Sources retain their recorded scope. A source link alone does not establish verification of every statement.
Evidence and review
What is flux balance analysis?: Stoichiometric steady-state constraints, feasible flux space and objective (indexed primary methodological passages)
2026-10-10 · Bounded author source inspection of flux-balance feasible spaces and objectives, including the stated conditions; independent branch review is recorded separately.
Entry details
Permanent link to this entry ↗- Record identity
- res-bio-flux-balance
- Revision
- research.1
- Structured reference record
- Postgraduate & research reference