Developmental induction and positional information
Signals from one embryonic region can influence cell fate in another.
Key knowledge
Signals from one embryonic region can influence cell fate in another. A localized signalling source can generate a spatial concentration gradient interpreted by competent receiving cells; different responses can pattern a tissue. Morphogen gradients are one mechanism of positional information alongside other interactions and inherited cell states.
Conditions and scope
- Response depends on competence, exposure and regulatory context, not concentration alone in every tissue.
- A diffusion-from-one-source example is not a universal mechanism of morphogen-gradient formation.
Sources · 1
References
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Evidence and review
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Entry details
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- University core expansion