Eukaryotic RNA maturation and alternative splicing
Many eukaryotic pre-mRNAs acquire a 5′ cap and 3′ poly(A) tail, and introns are removed while exons are joined.
Key knowledge
Many eukaryotic pre-mRNAs acquire a 5′ cap and 3′ poly(A) tail, and introns are removed while exons are joined. Alternative splice choices can generate different mature RNAs from one transcription unit. Untranslated regions remain in mature mRNA and can affect its regulation.
Conditions and scope
- Not every eukaryotic RNA is capped, polyadenylated or spliced in this pattern.
- An exon is a retained segment, not necessarily an entirely protein-coding segment.
Sources · 1
References
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Evidence and review
Read pre-mRNA cap, polyadenylation, intron/exon and splice-variant sections; retained coding/retention distinction.
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Entry details
Permanent link to this entry ↗- Record identity
- uni-bio-rna-processing
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- core.1
- Structured reference record
- University core expansion