Standard additions and matrix response
For identical sample aliquots diluted to a common final volume, blank-corrected linear response satisfies S=k(c₀V₀+cstdVstd)/Vf.
Key knowledge
For identical sample aliquots diluted to a common final volume, blank-corrected linear response satisfies S=k(c₀V₀+cstdVstd)/Vf. Regression against added concentration can infer the original sample concentration while calibrating in its matrix.
Values and equations
S = k(c₀V₀+cstdVstd)/Vf
- S
- blank-corrected analytical signal instrument signal unit
- k
- sensitivity signal unit m³ mol⁻¹
- c₀,cstd
- sample and added-standard concentrations mol m⁻³
- V₀,Vstd,Vf
- sample, added-standard and final volumes m³
Conditions and scope
- Added material must equilibrate and have the same response as native analyte; sensitivity and matrix remain effectively constant.
- Dilution, additive interference and nonlinear response require separate correction.
Sources · 1
References
Sources retain their recorded scope. A source link alone does not establish verification of every statement.
Evidence and review
Read standard-addition equations 5.7–5.8 and matrix restrictions.
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Entry details
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- uni-chem-standard-additions
- Revision
- core.1
- Structured reference record
- University core expansion