Fatty acid synthesis and malonyl units
In the canonical fatty-acid-synthase pathway, ATP-dependent acetyl-CoA carboxylation supplies malonyl units.
Key knowledge
In the canonical fatty-acid-synthase pathway, ATP-dependent acetyl-CoA carboxylation supplies malonyl units. Condensation, reduction, dehydration and reduction extend the carrier-bound chain by two carbons per cycle; reducing steps use NADPH. Synthesis is not simply β-oxidation run backwards.
Conditions and scope
- The reference illustrates cytosolic synthesis of palmitate; enzyme organization and compartments vary across organisms.
- Elongation, desaturation and other lipid synthesis need additional pathways.
Sources · 1
References
Sources retain their recorded scope. A source link alone does not establish verification of every statement.
Evidence and review
Read acetyl-CoA carboxylase/malonyl-CoA and carrier-bound condensation/reduction/dehydration/reduction panels; diagram text parsed, detailed stereochemical image not used.
2026-10-10 · Independent AI editorial review: All 115 actual compact claims, hypotheses, equation/variable/unit tables and 251 origin semantic links independently read. All exact author source-binding rows and disclosed extents assessed; targeted original bodies or specifically identified indexed primary passages rechecked below. All retained biology compact records read for combined breadth. Independent AI editorial content and practical common-core inventory review; no human specialist, degree/laboratory proficiency, whole-textbook certification or experimental replication. Receipt: biology-independent-content-inventory-review.1.
Entry details
Permanent link to this entry ↗- Record identity
- uni-bio-fatty-acid-synthesis
- Revision
- core.1
- Structured reference record
- University core expansion