Homology-directed recombination and repair
In homology-directed double-strand-break repair, end processing can produce single-stranded DNA that searches for and invades a homologous duplex.
Key knowledge
In homology-directed double-strand-break repair, end processing can produce single-stranded DNA that searches for and invades a homologous duplex. The intact sequence templates repair synthesis. Subsequent processing can yield crossover or noncrossover products; recombination also connects homologs during meiosis.
Conditions and scope
- This is a pathway family, not a guarantee that every repair is error-free.
- Available templates, cell-cycle state and intermediate processing affect the outcome.
Sources · 1
References
Sources retain their recorded scope. A source link alone does not establish verification of every statement.
Evidence and review
Read defining strand-invasion/repair-synthesis paragraph and crossover/noncrossover processing description; no exhaustive protein catalogue asserted.
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Entry details
Permanent link to this entry ↗- Record identity
- uni-bio-homologous-recombination
- Revision
- core.1
- Structured reference record
- University core expansion