Mutation flow and two-allele equilibrium
Mutation transfers allele copies between states.
Key knowledge
Mutation transfers allele copies between states. In a deterministic two-allele population without other frequency-changing forces, forward and backward mutation update the frequency by the surviving copies plus copies converted from the other allele. Positive rates in both directions give an interior equilibrium; mutation creates variation without necessarily producing rapid population change.
Values and equations
p′ = (1−u)p + v(1−p); peq = v/(u+v)
- p,p′
- frequency of allele A before and after mutation 1
- u
- probability of A→B mutation per generation 1 per generation
- v
- probability of B→A mutation per generation 1 per generation
- peq
- equilibrium A frequency when u+v>0 1
Conditions and scope
- The displayed recurrence specifies the per-generation mutation stage and omits selection, migration and drift.
- Rates are allele-specific model parameters; no fixed rate is universal across genes, species or mutation classes.
Sources · 1
References
Sources retain their recorded scope. A source link alone does not establish verification of every statement.
Evidence and review
Read forward/back mutation parameters and equilibrium u/(u+v); recurrence is direct copy-flow bookkeeping from those definitions. Excluded unlabelled continuous approximation as exact discrete solution, fixed mutation ranges and erroneous substitution-probability wording elsewhere in the notes.
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Entry details
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- uni-bio-mutation-recurrence
- Revision
- core.1
- Structured reference record
- University core expansion