Electrophilic aromatic substitution
In a typical electrophilic aromatic substitution, the aromatic π system bonds to an electrophile, forming a nonaromatic σ intermediate.
Key knowledge
In a typical electrophilic aromatic substitution, the aromatic π system bonds to an electrophile, forming a nonaromatic σ intermediate. Loss of a proton restores aromaticity with substitution rather than permanent addition. Substituents alter intermediate stabilization and therefore influence orientation and rate.
Conditions and scope
- Electrophile generation and the rate-controlling step depend on reaction conditions.
- Specific substituent effects and competing pathways need their own mechanistic evidence.
Sources · 2
References
Sources retain their recorded scope. A source link alone does not establish verification of every statement.
Evidence and review
Inspected σ-intermediate/restoration mechanism and activation/directing distinction.
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Entry details
Permanent link to this entry ↗- Record identity
- uni-chem-electrophilic-aromatic-substitution
- Revision
- core.1
- Structured reference record
- University core expansion